Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibody

Details for Product No. ABIN1105706
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Antigen
Synonyms A630044F12Rik, AI465270, AW229127, Cbfa2t3h, ETO-2, Eto2, MTGR2, MTG16a, MTG16b, ETO2, MTG16, ZMYND4
Epitope
N-Term
(4), (2), (1), (1)
Reactivity
Chicken, Human, Mouse (Murine), Rat (Rattus)
(15), (7), (3), (1)
Host
Rabbit
(13), (2)
Clonality
Polyclonal
Application
Western Blotting (WB)
(9), (8), (5), (4), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

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Catalog No. ABIN1105706
401.50 $
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Immunogen The immunogen for anti-CBFA2T3 antibody: synthetic peptide directed towards the N terminal of human CBFA2T3
Sequence QPRSTPPSMP PPPPAASQGA TRPPSFTPHT LMNGSSHSPT AINGAPCTPN
Purification Purified using peptide immunoaffinity column
Alternative Name CBFA2T3
Background The t(16,21)(q24,q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
Alternate names: MTG16, MTG8-related protein 2, MTGR2, Myeloid translocation gene on chromosome 16 protein, ZMYND4, Zinc finger MYND domain-containing protein 4
Gene ID 863
NCBI Accession NP_787127
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water to a final concentration of 1 mg/mL.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store lyophilized at 2-8°C or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for up to one month or in aliquots at -20°C long term.
Expiry Date 12 months
Background publications Powell, Gardner, Bais et al.: "Sequencing, transcript identification, and quantitative gene expression profiling in the breast cancer loss of heterozygosity region 16q24.3 reveal three potential tumor-suppressor genes." in: Genomics, Vol. 80, Issue 3, pp. 303-10, 2002 (PubMed).

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