Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibody

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Antigen
Synonyms A630044F12Rik, AI465270, AW229127, Cbfa2t3h, ETO-2, Eto2, MTGR2, MTG16a, MTG16b, ETO2, MTG16, ZMYND4
Epitope
N-Term
(5), (3), (2), (1), (1), (1)
Reactivity
Chicken, Human, Mouse (Murine), Rat (Rattus)
(25), (11), (5), (1)
Host
Rabbit
(21), (4)
Clonality
Polyclonal
Application
Western Blotting (WB)
(17), (14), (8), (5), (1)
Pubmed 1 reference available
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Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen The immunogen for anti-CBFA2T3 antibody: synthetic peptide directed towards the N terminal of human CBFA2T3
Sequence QPRSTPPSMP PPPPAASQGA TRPPSFTPHT LMNGSSHSPT AINGAPCTPN
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, ChickenSpecies reactivity (tested):Human
Purification Purified using peptide immunoaffinity column
Alternative Name CBFA2T3 (CBFA2T3 Antibody Abstract)
Background The t(16,21)(q24,q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.Synonyms: MTG16, MTG8-related protein 2, MTGR2, Myeloid translocation gene on chromosome 16 protein, ZMYND4, Zinc finger MYND domain-containing protein 4
Gene ID 863
NCBI Accession NP_787127
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Add 50 μL of distilled water to a final concentration of 1 mg/mL.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
Supplier Images
Western Blotting (WB) image for anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibody (ABIN1105706) Hum. Adult Placenta; Host: Rabbit. Target Name: CHAD . Sample Tissue: Human Adult Pla...
Western Blotting (WB) image for anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibody (ABIN1105706) Human Jurkat; WB Suggested Anti-CBFA2T3 Antibody Titration: 0.2-1 ug/ml. Positive Con...
Western Blotting (WB) image for anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibody (ABIN1105706) Human MCF7; Host: Rabbit. Target Name: NOP56 . Sample Tissue: MCF7 . Antibody Dilutio...
Background publications Powell, Gardner, Bais et al.: "Sequencing, transcript identification, and quantitative gene expression profiling in the breast cancer loss of heterozygosity region 16q24.3 reveal three potential tumor-suppressor genes." in: Genomics, Vol. 80, Issue 3, pp. 303-10, 2002 (PubMed).

Catalog No. ABIN1105706
$401.50
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