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CCR1 antibody (C-C Chemokine Receptor Type 1) (PE)

Details for Product anti-CCR1 Antibody No. ABIN1105988, Supplier: Log in to see
Antigen
  • CD191
  • CKR-1
  • CKR1
  • CMKBR1
  • HM145
  • MIP1aR
  • SCYAR1
  • Cmkbr1
  • Mip-1a-R
Reactivity
Human
81
18
3
3
1
Host
Mouse
59
15
8
6
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CCR1 antibody is conjugated to PE
7
6
6
2
2
2
2
1
Application
Flow Cytometry (FACS)
60
43
35
26
18
2
2
2
2
2
1
1
1
1
Supplier
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Immunogen Human PBMC (peripheral blood mononuclear cell) CCR-1
Clone 141-2
Isotype IgG1
Specificity This antibody reacts with CCR1.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein-A Sepharose
Alternative Name CD191 / CCR1 (CCR1 Antibody Abstract)
Background Chemokines, which are a group of 70 to 90 amino acid structurally-related polypeptides, were first isolated as the regulation factors of leukocyte recirculation and Synonyms: C-C CKR-1, C-C chemokine receptor type 1, CC-CKR-1, CCR-1, CMKBR1, CMKR1, HM145, LD78 receptor, MIP1 alpha Receptor, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, SCYAR1
Gene ID 1230
NCBI Accession NP_001286
UniProt P32246
Research Area Chemokines, Receptors
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 10 µg/mL
Buffer PBS, 0.09 % NaN3, 1 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2 - 8 °C.
Supplier Images
Flow Cytometry (FACS) image for anti-CCR1 antibody (C-C Chemokine Receptor Type 1)  (PE) (ABIN1105988) anti-C-C Chemokine Receptor Type 1 (CCR1) antibody (PE)
Background publications Rosen: "Homing in on L-selectin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 1, pp. 3-4, 2006 (PubMed).

Sato, Fujiwara, Zeng et al.: "Platelet-derived soluble factors induce human extravillous trophoblast migration and differentiation: platelets are a possible regulator of trophoblast infiltration into maternal spiral arteries." in: Blood, Vol. 106, Issue 2, pp. 428-35, 2005 (PubMed).

Sato, Higuchi, Yoshioka et al.: "Trophoblasts acquire a chemokine receptor, CCR1, as they differentiate towards invasive phenotype." in: Development (Cambridge, England), Vol. 130, Issue 22, pp. 5519-32, 2003 (PubMed).

Sato, Kawasaki, Morimoto et al.: "An abortive ligand-induced activation of CCR1-mediated downstream signaling event and a deficiency of CCR5 expression are associated with the hyporesponsiveness of human naive CD4+ T cells to CCL3 and CCL5." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 12, pp. 6263-72, 2002 (PubMed).

Sato, Kawasaki, Nagayama et al.: "Chemokine receptor expressions and responsiveness of cord blood T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 3, pp. 1659-66, 2001 (PubMed).

Sato, Kawasaki, Nagayama et al.: "Signaling events following chemokine receptor ligation in human dendritic cells at different developmental stages." in: International immunology, Vol. 13, Issue 2, pp. 167-79, 2001 (PubMed).

Rollins: "Chemokines." in: Blood, Vol. 90, Issue 3, pp. 909-28, 1997 (PubMed).

Curtis: "Defending attacks on statistics." in: Nature medicine, Vol. 2, Issue 1, pp. 4-5, 1996 (PubMed).

Baggiolini, Dewald, Moser: "Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines." in: Advances in immunology, Vol. 55, pp. 97-179, 1994 (PubMed).

Kelner, Kennedy, Bacon et al.: "Lymphotactin: a cytokine that represents a new class of chemokine." in: Science (New York, N.Y.), Vol. 266, Issue 5189, pp. 1395-9, 1994 (PubMed).

Oppenheim, Zachariae, Mukaida et al.: "Properties of the novel proinflammatory supergene \intercrine\' cytokine family.'" in: Annual review of immunology, Vol. 9, pp. 617-48, 1991 (PubMed).

Miller, Krangel: "Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines." in: Critical reviews in immunology, Vol. 12, Issue 1-2, pp. 17-46, 1992 (PubMed).