CCR1 antibody

Catalog No. ABIN5611256

Product Details anti-CCR1 Antibody

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCR1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human CD191 (AA: extra mix) expressed in E. coli.

Clone: 8E10F9

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for CCR1

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Alternative Name: CD191 (CCR1 Products)

Synonyms: CD191 antibody, CKR-1 antibody, CKR1 antibody, CMKBR1 antibody, HM145 antibody, MIP1aR antibody, SCYAR1 antibody, Cmkbr1 antibody, Mip-1a-R antibody, C-C motif chemokine receptor 1 antibody, chemokine (C-C motif) receptor 1 antibody, CCR1 antibody, Ccr1 antibody

Background:

Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.

Aliases: CCR1, CKR1, CKR-1, HM145, CMKBR1, MIP1aR, SCYAR1

Molecular Weight: 41.2 kDa

Gene ID: 1230

HGNC: 1230