CCR1 antibody (Chemokine (C-C Motif) Receptor 1)

Details for Product anti-CCR1 Antibody No. ABIN5611255
Antigen
Reactivity
Human
108
29
3
3
Host
Mouse
95
12
8
6
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CCR1 antibody is un-conjugated
9
8
7
6
3
2
2
2
2
2
2
2
Application
ELISA, Flow Cytometry (FACS), Western Blotting (WB)
73
49
43
36
28
6
6
4
3
2
2
2
Options
Immunogen Purified recombinant fragment of human CD191 (AA extra mix) expressed in E. Coli.
Clone 8E10G6
Isotype IgG1
Antigen
Alternative Name CD191 (CCR1 Antibody Abstract)
Background This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
Molecular Weight 41.2kDa
HGNC 1230
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N:A, FCM: 1:200 - 1:400, IHC: N:A
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Chemokine (C-C Motif) Receptor 1 (CCR1) antibody (ABIN5611255) Flow cytometric analysis of Ramos cells using CD191 mouse mAb (green) and negative co...
Image no. 2 for anti-Chemokine (C-C Motif) Receptor 1 (CCR1) antibody (ABIN5611255) Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen ...
Image no. 3 for anti-Chemokine (C-C Motif) Receptor 1 (CCR1) antibody (ABIN5611255) Western blot analysis using CD191 mAb against human CD191 (AA: extra mix) recombinant...
Image no. 4 for anti-Chemokine (C-C Motif) Receptor 1 (CCR1) antibody (ABIN5611255) Western blot analysis using CD191 mAb against HEK293 (1) and CD191 (AA: extra mix)-hI...