IL-6 antibody
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- Target See all IL-6 (IL6) Antibodies
- IL-6 (IL6) (Interleukin 6 (IL6))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IL-6 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Functional Studies (Func)
- Specificity
- Recognises both natural and recombinant Human IL-6
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Ion Exchange Chromatography
- Sterility
- 0.22 μm filtered
- Immunogen
- Human recombinant IL-6.
- Clone
- B-E8
- Isotype
- IgG1
- Top Product
- Discover our top product IL6 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free
- Preservative
- Without preservative
- Storage
- 4 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C.
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- Target
- IL-6 (IL6) (Interleukin 6 (IL6))
- Alternative Name
- Interleukin-6 (IL6) (IL6 Products)
- Background
- Interleukin 6 (IL6) is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6 has also been implicated in regulating adipose mass.Synonyms: B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFNB2, IL-6, Interferon beta-2
- Gene ID
- 3569
- NCBI Accession
- NP_000591
- UniProt
- P05231
- Pathways
- TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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