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beta-2 Microglobulin antibody

B2M Reactivity: Human FACS, IF, IHC (fro) Host: Mouse Monoclonal B1G6 unconjugated
Catalog No. ABIN111076
  • Target See all beta-2 Microglobulin (B2M) Antibodies
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    Reactivity
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    Human
    Host
    • 126
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    Mouse
    Clonality
    • 127
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    Monoclonal
    Conjugate
    • 111
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    This beta-2 Microglobulin antibody is un-conjugated
    Application
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Human beta 2-Microglobulin (MW 12 kDa). Recognizes the HLA-beta 2-Microglobulin complex, free or associated with the membrane. Does not react with other species. The exact epitope for the antibody has not been mapped.
    Purification
    Protein A Chromatography
    Immunogen
    Purified human Beta 2-Microglobulin
    Clone
    B1G6
    Isotype
    IgG2a
    Top Product
    Discover our top product B2M Primary Antibody
  • Application Notes
    Purification of the HLA antigens associated with beta 2-Microglobulin. Fluorescence Microscopy or Flow Cytometry: 2 μg/5x10e5 cells/test. Immunohistochemistry (Frozen Sections or Cell Smears): 1/25-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 1.0 mL distilled water
    Concentration
    0.2 mg/mL (prior to lyophilization)
    Buffer
    PBS, None, 1 mg/mL BSA
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Prior to reconstitution store at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Following reconstitution store the antibody at -20 °C.
  • Target
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    Alternative Name
    beta-2-Microglobulin (B2M Products)
    Background
    Beta-2 Microglobulin non-covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.Synonyms: B2M, Beta 2 microglobulin, Beta-2 microglobulin
    Gene ID
    567
    NCBI Accession
    NP_004039
    UniProt
    P61769
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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