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beta-2 Microglobulin antibody (beta-2-Microglobulin) (AA 21-100) Primary Antibody

B2M Reactivity: Human FACS, IHC, ELISA, WB Host: Mouse Monoclonal 3G5H8 unconjugated
Pubmed (2)
Catalog No. ABIN1724930
$448.80
Plus shipping costs $45.00
0.1 mg
local_shipping Shipping to: United States
Delivery in 3 to 4 Business Days
  • Target
    beta-2 Microglobulin (B2M)
    Binding Specificity
    AA 21-100
    • 18
    • 14
    • 12
    • 10
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivity
    Human
    • 240
    • 52
    • 52
    • 52
    • 12
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Host
    Mouse
    • 150
    • 120
    • 11
    • 9
    • 3
    • 1
    Clonality
    Monoclonal
    Conjugate
    This beta-2 Microglobulin antibody is un-conjugated
    • 125
    • 35
    • 22
    • 15
    • 13
    • 10
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    • 147
    • 145
    • 96
    • 77
    • 74
    • 49
    • 39
    • 38
    • 33
    • 27
    • 17
    • 13
    • 11
    • 9
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Purification
    Purified
    Immunogen
    Purified recombinant fragment of human B2M (AA 21-100) expressed in E. Coli.
    Clone
    3G5H8
    Isotype
    IgG2a
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Bernal, Ruiz-Cabello, Concha, Paschen, Garrido: "Implication of the ?2-microglobulin gene in the generation of tumor escape phenotypes." in: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 9, pp. 1359-71, 2012 (PubMed).

    Hermansen, Hummelshøj, Lundsgaard, Hornum, Keller, Fleckner, Fox, Poulsen, Jacobsen: "Increased serum ?2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus patients." in: Lupus, Vol. 21, Issue 10, pp. 1098-104, 2012 (PubMed).

  • Target
    beta-2 Microglobulin (B2M)
    Alternative Name
    B2M (B2M Antibody Abstract)
    Synonyms
    Ly-m11, beta2-m, beta2m, bwm, wu:fa94c05, wu:fb10a09, b2m-W01, b2m-W03, b2m-Z01, b2m-Z02, b2m-Z03, B2M, b2m, B2MG, b-2-m, beta-2-microglobulin, beta-2 microglobulin, beta-2-microglobulin S homeolog, B2M, B2m, b2m, b2m.S
    Background
    This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. ,
    Molecular Weight
    13.7 kDa
    Gene ID
    567
    HGNC
    567
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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