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CD137 antibody
TNFRSF9
Reactivity: Mouse
FACS, WB
Host: Rat
Monoclonal
M4173
unconjugated
Product Details anti-CD137 Antibody
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Target
See all CD137 (TNFRSF9) Antibodies
CD137 (TNFRSF9)
(Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
Reactivity
All reactivities for CD137 antibodies
Mouse
Host
All hosts for CD137 antibodies
Rat
Clonality
All clonalities for CD137 antibodies
Monoclonal
Conjugate
All conjugates for CD137 antibodies
This CD137 antibody is un-conjugated
Application
All applications for CD137 antibodies
Flow Cytometry (FACS), Western Blotting (WB)
Specificity
Recognizes mouse CD137. Detects a band of ~40 kDa by Western blot.
Cross-Reactivity
Mouse (Murine)
No Cross-Reactivity
Human
Cross-Reactivity (Details)
Does not cross-react with human CD137.
Sterility
0.2 μm filtered
Immunogen
Recombinant mouse CD137.
Clone
M4173
Isotype
IgG1
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Preservative
Without preservative
Storage
4 °C,-20 °C
Storage Comment
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date
12 months
Target Details for CD137
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Target
CD137 (TNFRSF9)
(Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
Alternative Name
CD137 (TNFRSF9 Products )
Background
CD137 is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.
UniProt
P20334
Pathways
Cancer Immune Checkpoints
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