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CD57 antibody (FITC)
B3GAT1
Reactivity: Human
FACS
Host: Mouse
Monoclonal
TB01
FITC
Product Details anti-CD57 Antibody (FITC)
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Target
See all CD57 (B3GAT1) Antibodies
CD57 (B3GAT1)
(beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))
Reactivity
All reactivities for CD57 antibodies
Human
Host
All hosts for CD57 antibodies
Mouse
Clonality
All clonalities for CD57 antibodies
Monoclonal
Conjugate
All conjugates for CD57 antibodies
This CD57 antibody is conjugated to FITC
Application
All applications for CD57 antibodies
Flow Cytometry (FACS)
Purification
Ion exchange chromatography
Immunogen
Human neuroblastoma cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3.X63.Ag8653 myeloma cell line.
Clone
TB01
Isotype
IgM
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Alternatives
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Application Details
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Application Notes
Flow cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0.1 mg/mL
Buffer
PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for CD57
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Target
CD57 (B3GAT1)
(beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))
Alternative Name
CD57 / HNK1 (B3GAT1 Products )
Background
CD57 recognizes a (Mr 100-110 kDa) oligosaccharide antigenic determinant on myeloid cells and on a variety of polypeptides, lipids and chondroitan sulfate proteoglycans. This surface antigen is associated with myelin-associated glycoprotein (MAG). The CD57 antigen is present on 15-20 % of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60 %) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system.Synonyms: HNK-1, LEU7, NK-1, NK-Cell marker, NK1
Gene ID
27087
UniProt
Q9P2W7
Pathways
Glycosaminoglycan Metabolic Process
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