CTLA4 antibody
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- Target See all CTLA4 Antibodies
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CTLA4 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- Specificity
- Highly specific for CD152 (CTAL-4).
- Immunogen
- Human CTLA-4/human IgG heavy chain fusion protein (CTLA-4/Ig)
- Clone
- BNI3
- Isotype
- IgG2a
- Top Product
- Discover our top product CTLA4 Primary Antibody
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anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibody (PE)
CTLA4 Reactivity: Human FACS Host: Mouse Monoclonal BNI3 PE
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-135) antibodyCTLA4 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 2F1 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibodyCTLA4 Reactivity: Human FACS, IP, ICC, IHC (fro) Host: Mouse Monoclonal BNI3 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibodyCTLA4 Reactivity: Human FACS, IP, ICC, IHC (fro) Host: Mouse Monoclonal BNI3 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-162) antibodyCTLA4 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 9D2E9 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) antibodyCTLA4 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 8B3F8 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) antibodyCTLA4 Reactivity: Human FACS, ELISA Host: Rabbit Monoclonal DM50 unconjugated Recombinant Antibody
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 41-90) antibodyCTLA4 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 52-211) antibodyCTLA4 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 75-170) antibodyCTLA4 Reactivity: Human, Mouse, Rat FACS, WB, ELISA, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Research studies by Microscopy or Flow cytometry, after in vitro activation of T cells with selected stimuli (Concanavalin A, or solid-phase fixed-CD3 + CD28 Mabs stimulation). Research studies on CTLA-4 expression on B cells and on CTLA-4 expression by Immunohistochemistry only on frozen tissue sections. Fluorescence microscopy or Flow cytometry: 2 μg/5x10e5 cells/test. Cytospin or immunohistochemistry on frozen tissue sections: Working concentration is 5-50 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore with 1 mL of distilled water.
- Buffer
- PBS, pH 7.2, containing 1 mg/mL BSA as stabilizer without preservatives
- Preservative
- Without preservative
- Storage
- 4 °C
- Storage Comment
- Store at 2 - 8 °C.
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- Target
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
- Alternative Name
- CD152 / CTLA4 (CTLA4 Products)
- Background
- The cytolytic T-lymphocyte-associated antigen 4 (CTLA-4) is a member of the Ig superfamily (1) and its extracellular domain exhibits a single Ig V-like region. It was originally identified as a fourth cDNA product, during a search for genes that were thought to be specifically expressed in cytotoxic T lymphocytes (1). CTLA-4 has a molecular weight close to 45 kDa (2). It is mainly expressed as a monomer (4), but may also be expressed as a disulfide-linked homodimer (2,3). CTLA-4 belongs to the CD28 receptor family (4,5).Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
- Gene ID
- 1493
- NCBI Accession
- NP_001032720
- UniProt
- P16410
- Pathways
- Cancer Immune Checkpoints
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