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Integrin beta 3 antibody

ITGB3 Reactivity: Mouse, Rat FACS, IP Host: Hamster Monoclonal HM beta 3-1 unconjugated
Catalog No. ABIN120250
  • Target See all Integrin beta 3 (ITGB3) Antibodies
    Integrin beta 3 (ITGB3)
    Reactivity
    • 180
    • 91
    • 59
    • 16
    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 120
    • 63
    • 10
    • 2
    Hamster
    Clonality
    • 115
    • 78
    Monoclonal
    Conjugate
    • 102
    • 16
    • 11
    • 10
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin beta 3 antibody is un-conjugated
    Application
    • 122
    • 84
    • 53
    • 46
    • 28
    • 28
    • 23
    • 19
    • 15
    • 13
    • 13
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Purification
    Affinity Chromatography on Protein G.
    Immunogen
    Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4. Spleen cells from immunised Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line.
    Clone
    HM beta 3-1
    Isotype
    IgG
    Top Product
    Discover our top product ITGB3 Primary Antibody
  • Application Notes
    Flow Cytometry: Use 10 μL of 1/10-1/25 diluted antibody to label 10^6 cells in 100 μL. Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Integrin beta 3 (ITGB3)
    Alternative Name
    CD61 / ITGB3 (ITGB3 Products)
    Background
    CD61 is a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptor for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
    Gene ID
    10090
    UniProt
    O54890
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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