anti-Cyclin A antibody (Cyclin A2)

Details for Product anti-CCNA2 Antibody No. ABIN121516
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Synonyms ccn1, ccna, ccna1, CCN1, CCNA, AA408589, Ccn-1, Ccn1, Ccna, CycA2, Cyca, cb671, chunp6924, wu:fi36f03, CYCA, Cyclin-A2, ccna2, Cyclin-A, cyclinA
Human, Mouse (Murine), Rat (Rattus)
(137), (40), (31), (26), (3), (3), (2), (2), (2), (2), (2), (1), (1)
(98), (67), (1)
This Cyclin A antibody is un-conjugated
(2), (1), (1)
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(139), (63), (44), (41), (36), (31), (17), (8), (8), (4), (4), (3), (2), (1), (1), (1)
Pubmed 3 references available
Quantity 0.1 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Full length GST fusion protein corresponding to the human cyclin A gene
Specificity This product was prepared from monospecific antiserum by delipidation and defibrination. Antiserum will specifically react with a 60 kDa Cyclin A protein from Human, Rat and Mouse tissue. No reaction was observed against other related Cyclins. Cross reactivity with Cyclin A from other species may also occur.
Cross-Reactivity (Details) Species reactivity (tested):Human, Rat and Mouse.
Purification Delipidation and defibrination.
Alternative Name Cyclin A2 (CCNA2 Antibody Abstract)
Background Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin / cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S phase and passage through G2 phase.Synonyms: CCN1, CCNA, CCNA2, Cyclin A, Cyclin-A2
UniProt P20248
Research Area Cell Cycle
Pathways PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling
Application Notes Immunoprecipitation. ELISA: 1/500-1/2000. Western blot: 1/250-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 80 mg/mL (by Refractometry)
Storage 4 °C/-20 °C
Storage Comment Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Expiry Date 12 months
Background publications Giordano, Whyte, Harlow et al.: "A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells." in: Cell, Vol. 58, Issue 5, pp. 981-90, 1989 (PubMed).

Pines, Hunter: "Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B." in: Nature, Vol. 346, Issue 6286, pp. 760-3, 1990 (PubMed).

Wang, Chenivesse, Henglein et al.: "Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma." in: Nature, Vol. 343, Issue 6258, pp. 555-7, 1990 (PubMed).

Catalog No. ABIN121516
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