EIF3K antibody (AA 121-218) (FITC)

Catalog No. ABIN1394912

Product Details anti-EIF3K Antibody (FITC)

Target: EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))

Binding Specificity: AA 121-218

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3K antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human eIF3K

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EIF3K

Target: EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))

Alternative Name: e3K (EIF3K Products)

Background:

Synonyms: ARG134, e 3 p25, e 3 p28, e-3 p25, e-3 p28, E3-p28, e3k, e3k, E3K_HUMAN, E3S12, Eukaryotic translation initiation factor 3 subunit 12, Eukaryotic translation initiation factor 3 subunit K, HSPC029, M9, MSTP001, Muscle specic gene M9 protein, Muscle-specic gene M9 protein, PLAC 24, PLAC-24, PLAC24, PRO1474, PTD001, E3K_HUMAN.

Background: eIF3K (Eukaryotic translation initiation factor 3 subunit K, Muscle-specific gene M9 protein) is a widely expressed translation initiation factor that belongs to the eIF3 subunit K family. Translation initiation factor 3 (eIF3) is a multisubunit complex containing at least 12 subunits. eIF3 binds to the 40S ribosomal subunit, promotes the binding of methionyl-tRNAi and mRNA, and interacts with several other initiation factors to form the 40S initiation complex. eIF3K is the smallest subunit of eIF3 and it interacts with several other subunits of eIF3 and the 40S ribosomal subunit. eIF3K is conserved among high eukaryotes, including mammals, insects, and plants, and it is ubiquitously expressed in human tissues. eIF3K is distributed both in nucleus and cytoplasm and colocalizes with cyclin D3, a regulatory subunit of cyclin-dependent kinase 4 (Cdk4).

Pathways: Ribonucleoprotein Complex Subunit Organization