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PD-L1 antibody (Extracellular Domain) (PE)

Name: PD-L1 antibody (Extracellular Domain) (PE)
SKU: ABIN1449172
Price: 620.4 USD
Availability: InStock

PD-L1 Reactivity: Human FACS Host: Mouse Monoclonal J110 PE

FACS

1 image

Catalog No. ABIN1449172

Datasheet as PDF

Target See all PD-L1 Antibodies

PD-L1 (CD274 (PD-L1))
Binding Specificity
29

16

15

11

10

8

7

7

6

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Extracellular Domain
Reactivity
166

117

62

6

5

5

5

1

1
Human
Host
130

54

20

4

4

2
Mouse
Compatible Secondaries
Clonality
111

98

5
Monoclonal
Conjugate
98

15

12

10

8

5

4

4

4

4

4

4

4

4

4

4

4

3

3

2

2

2

2

2

2

2

1

1
This PD-L1 antibody is conjugated to PE
Application
129

107

59

41

40

28

18

17

15

14

10

7

6

4

3

3

2

2

1

1

1

1
Flow Cytometry (FACS)

Specificity

This antibody reacts with human PD-1.

Purification

Protein A agarose

Immunogen

Fusion protein of the extracellular domain of human PD-1 and the constant region of human gamma1 heavy chain

Clone

J110

Isotype

IgG1

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Verified PD-L1 Reactivity: Human WB, FACS, ELISA, IF Host: Goat Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 Reactivity: Human WB, FACS, IHC, ELISA, IF Host: Mouse Monoclonal 9B5F4 unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 Reactivity: Human FACS, IHC, ELISA Host: Mouse Monoclonal 6D9A2 unconjugated

anti-CD274 (PD-L1) (AA 39-191) antibody
PD-L1 Reactivity: Human, Mouse WB, FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal PDL1-2746 unconjugated

anti-CD274 (PD-L1) (AA 48-290) antibody
PD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 34-241) antibody
PD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 7D2A10 unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
KO Validated PD-L1 Reactivity: Human WB, FACS, IF, ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 201-290) antibody
PD-L1 Reactivity: Mouse, Rat WB, ELISA, IF (cc), IHC (p), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Buffer

PBS, 0.09 % NaN3, 1 % BSA

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Storage Comment

Store at 2-8 °C.
Target

PD-L1 (CD274 (PD-L1))

Alternative Name

CD274 / PDL1 (PD-L1 Products)

Background

Human PD-1 (programmed death-1) is a 55 kDa member of the immunoglobulin superfamily that is induced in cells undergoing apoptosis. The PD-1 protein contains an immunoreceptor tyrosine-based inhibitory motif and is expressed predominantly on activated T and B lymphocytes. PD-1 plays a key role in peripheral tolerance and autoimmune diseases and is thought to be involved in the maintenance of peripheral self-tolerance by serving as a negative regulator of immune responses. Two novel members of the B7 family have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and up-regulation on activated antigen presenting cells.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1

Gene ID

29126

NCBI Accession

NP_054862

UniProt

Q9NZQ7

Pathways

Cancer Immune Checkpoints