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RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody

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Antigen
Alternatives
Epitope
N-Term
(17), (9), (6), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(66), (18), (16), (9), (3), (3), (2), (2), (1)
Host
Rabbit
(50), (16)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(55), (23), (22), (17), (12), (8), (4), (2), (1), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the N terminal of human RUVBL2
Sequence IERIGAHSHI RGLGLDDALE PRQASQGMVG QLAARRAAGV VLEMIREGKI
Predicted Reactivity Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, African clawed frog : 90 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against RUVBL2. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name RUVBL2 (RUVBL2 Antibody Abstract)
Background RuvB-Like 2 (48-kDa TATA box-binding protein-interacting protein, Reptin 52, RUVBL2) is the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this protein has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
Molecular Weight 51 kDa
Gene ID 10856
NCBI Accession NP_006657, NM_006666
UniProt Q9Y230
Pathways Telomere Maintenance
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 463 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody (ABIN182548) WB Suggested Anti-RUVBL2 Antibody Titration: 2.0-4.0ug/ml
Positive Contr...
Immunohistochemistry (IHC) image for anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody (ABIN182548) anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody (ABIN182548) anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody (Image 3)
Western Blotting (WB) image for anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody (ABIN182548) Sample Type: Lane 1:241 µg untransfected H1299 cells Lane 2: 041 µg siRUVBL2 transfec...
Immunohistochemistry (IHC) image for anti-RuvB-Like 2 (E. Coli) (RUVBL2) (N-Term) antibody (ABIN182548) Human urinary bladder
Background publications Bauer, Chauvet, Huber et al.: "Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity." in: The EMBO journal, Vol. 19, Issue 22, pp. 6121-30, 2000 (PubMed).

Catalog No. ABIN182548

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