RUVBL2 antibody (N-Term)

Catalog No. ABIN2779601

There is 1 publication for this product available. The Rabbit Polyclonal anti-RUVBL2 antibody is suitable to detect RUVBL2 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB and IHC.

Quick Overview for RUVBL2 antibody (N-Term) (ABIN2779601)

Target: RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUVBL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RUVBL2 Antibody

Binding Specificity: N-Term

Purpose: RUVBL2 Antibody - N-terminal region

Sequence: IDRPATGTGS KVGKLTLKTT EMETIYDLGT KMIESLTKDK VQAGDVITID

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RUVBL2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RUVBL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8111062

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-RUVBL2 antibody (ABIN2779601)

Barthéléry, Jaishankar, Salli, Vrana: "Reptin52 expression during in vitro neural differentiation of human embryonic stem cells." in: Neuroscience letters, Vol. 452, Issue 1, pp. 47-51, (2009) (PubMed).

Target Details for RUVBL2

Target: RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))

Alternative Name: RUVBL2

Background:

Background Information: RUVBL2 encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities.

Gene Name: RuvB-like 2 (E. coli)

Alternative Symbols: RVB2, TIH2, ECP51, TIP48, CGI-46, ECP-51, INO80J, REPTIN, TIP49B, TAP54-beta

Protein Name: RuvB-like 2

Molecular Weight: 51kDa

Gene ID: 10856

NCBI Accession: NP_006657

UniProt: Q9Y230

Pathways: Telomere Maintenance