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Details for Product No. ABIN182562

TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (N-Term) antibody

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Synonyms 1110030N06Rik, A530078N03Rik, Map3k7ip2, mKIAA0733, MAP3K7IP2, CHTD2
»Alternatives N-Term
»Alternatives Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Human, Chicken
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN182562
Quantity 50 µg
289.00 $   Plus shipping costs $45.00
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Immunogen The immunogen for anti-MAP3K7IP2 antibody: synthetic peptide directed towards the N terminal of human MAP3K7IP2
Predicted Reactivity Mouse :100%,   Bovine :100%,   Dog :100%,   Rat :100%,   Human :100%,   Chicken :85%,  
Characteristics This is a rabbit polyclonal antibody against MAP3K7IP2. It was validated on Western Blot and immunohistochemistry. We manufacture rabbit polyclonal antibodies on a large scale of high throughput manner. Our antibodies are peptide based and protein family oriented.
Purification Affinity Purified
Alternative Name MAP3K7IP2
Background MAP3K7IP2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of NF.:B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serving as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF.:B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
Molecular Weight 76kDa
Gene ID 23118
NCBI Accession NP_055908, NM_015093
UniProt Q9NYJ8
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-MAP3K7IP2 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Kanayama, Seth, Sun et al.: "TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains." in: Molecular cell, Vol. 15, Issue 4, pp. 535-48, 2004 (PubMed).

Alternatives for antigen "TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2)", type "Antibodies"
Hosts (16), (10), (6)
Reactivities (31), (5), (4), (3), (2)
Applications (17), (15), (10), (9), (6), (4), (2), (1), (1), (1)
Epitopes (9), (3), (3), (2), (1), (1)