Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1) (N-Term) antibody

Details for Product No. ABIN182817
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Antigen
Synonyms
WHSC1, fc12c04, wu:fc12c04, wu:fi20c01, si:rp71-77d7.2, whs, nsd2, trx5, mmset, reiibp, MMSET, NSD2, REIIBP, TRX5, WHS, RGD1565590, 5830445G22Rik, 9430010A17Rik, AW555663, C130020C13Rik, D030027O06Rik ... show more
WHSC1, fc12c04, wu:fc12c04, wu:fi20c01, si:rp71-77d7.2, whs, nsd2, trx5, mmset, reiibp, MMSET, NSD2, REIIBP, TRX5, WHS, RGD1565590, 5830445G22Rik, 9430010A17Rik, AW555663, C130020C13Rik, D030027O06Rik, D930023B08Rik, Whsc1l, mKIAA1090 show less
Epitope
N-Term
(8), (7), (3), (2), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human, Chicken
(18), (2), (2), (2)
Host
Rabbit
(15), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(15), (8), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN182817
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human WHSC1
Sequence KYNVGDLVWS KVSGYPWWPC MVSADPLLHS YTKLKGQKKS ARQYHVQFFG
Predicted Reactivity Chicken : 100 %, Horse : 100 %, Human : 100 %, Guinea pig : 80 %, Mouse : 80 %, Dog : 70 %, Rabbit : 70 %
Characteristics This is a rabbit polyclonal antibody against WHSC1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name WHSC1
Background WHSC1 encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4.
Molecular Weight 88 kDa
Gene ID 7468
NCBI Accession NM_014919, NP_055734
UniProt O96031
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 802 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1) (N-Term) antibody WB Suggested Anti-WHSC1 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
Background publications Santra, Zhan, Tian et al.: "A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript." in: Blood, Vol. 101, Issue 6, pp. 2374-6, 2003 (PubMed).

Validation Images
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