GLIS Family Zinc Finger 3 (GLIS3) (N-Term) antibody

Details for Product No. ABIN183860
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Antigen
Synonyms ZNF515, E230012L24, 4833409N03Rik, E330013K21Rik, GLIS3, wu:fa55a05, zgc:158249, glis3, pc
Epitope
N-Term
(2), (1)
Reactivity
Dog (Canine), Mouse (Murine), Rat (Rattus), Human
(6), (1), (1)
Host
Rabbit
(6)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(6)
Pubmed 1 reference available
Catalog no. ABIN183860
Quantity 100 µg
Price
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Immunogen Synthetic peptide directed towards the N terminal of human GLIS3
Sequence PPASQVSTACNQISPSLQRAMNAANLNIPPSDTRSLISRE SLASTTLSLT
Predicted Reactivity Horse : 100 %, Human : 100 %, Mouse : 90 %
Characteristics This is a rabbit polyclonal antibody against GLIS3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name GLIS3
Background GLIS3 is a member of the GLI-similar zinc finger protein family and has five C2H2-type zinc finger domains. GLIS3 functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH).
Molecular Weight 84 kDa
Gene ID 169792
NCBI Accession NM_152629, NP_689842
UniProt Q8NEA6
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 775 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-GLIS Family Zinc Finger 3 (GLIS3) (N-Term) antibody WB Suggested Anti-GLIS3 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
Background publications Kim, Nakanishi, Lewandoski et al.: "GLIS3, a novel member of the GLIS subfamily of Krüppel-like zinc finger proteins with repressor and activation functions." in: Nucleic acids research, Vol. 31, Issue 19, pp. 5513-25, 2003 (PubMed).

Hosts (6)
Reactivities (6), (1), (1)
Applications (6)
Epitopes (2), (1)
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