GLIS3 antibody (N-Term)

Catalog No. ABIN2778522

Product Details anti-GLIS3 Antibody

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Dog, Rat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PPASQVSTAC NQISPSLQRA MNAANLNIPP SDTRSLISRE SLASTTLSLT

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GLIS3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLIS3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 775 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GLIS3

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Alternative Name: GLIS3 (GLIS3 Products)

Synonyms: ZNF515 antibody, 4833409N03Rik antibody, E230012L24 antibody, E330013K21Rik antibody, GLIS3 antibody, wu:fa55a05 antibody, zgc:158249 antibody, glis3 antibody, pc antibody, RGD1565505 antibody, GLIS family zinc finger 3 antibody, GLIS3 antibody, Glis3 antibody, glis3 antibody

Background: GLIS3 is a member of the GLI-similar zinc finger protein family and has five C2H2-type zinc finger domains. GLIS3 functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH).
Alias Symbols: ZNF515
Protein Interaction Partner: SUFU, SOX2,
Protein Size: 775

Molecular Weight: 84 kDa

Gene ID: 169792

NCBI Accession: NM_152629, NP_689842

UniProt: Q8NEA6