GLIS3 antibody (AA 606-775)

Catalog No. ABIN6141131

The Rabbit Polyclonal anti-GLIS3 antibody is suitable to detect GLIS3 in samples from Human. It has been validated for WB.

Quick Overview for GLIS3 antibody (AA 606-775) (ABIN6141131)

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIS3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GLIS3 Antibody

Binding Specificity: AA 606-775

Sequence: DAGAERFAPS APSPHHISPR RVPAPSSILQ RTQPPYTQQP SGSHLKSYQP ETNSSFQPNG IHVHGFYGQL QKFCPPHYPD SQRIVPPVSS CSVVPSFEDC LVPTSMGQAS FDVFHRAFST HSGITVYDLP SSSSSLFGES LRSGAEDATF LQISTVDRCP SQLSSVYTEG

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 606-775 of human GLIS3 (NP_689842.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GLIS3

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Alternative Name: GLIS3

Background: This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.,GLIS3,NDH,ZNF515,Epigenetics & Nuclear Signaling,Transcription Factors,GLIS3

Molecular Weight: 83 kDa/99 kDa

Gene ID: 169792

UniProt: Q8NEA6