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Details for Product No. ABIN183955

Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) (C-Term) antibody

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Antigen
Synonyms
RNPU1Z, RPU1, SNRP70, Snp1, U1-70K, U170K, U1AP, U1RNP, snrp70, 2700022N21Rik, 3200002N22Rik, 70kDa, AI325098, R74807, Rnulp70, Snrp70, Srnp70, U1-70, wu:fc20b04, zgc:136450, rnpu1z, rpu1, u170k, u1ap ... show more
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Cow (Bovine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN183955
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-SNRP70 antibody: synthetic peptide directed towards the C terminal of human SNRP70
Sequence RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGP DGPEEKGRDR
Predicted Reactivity Bovine :100%,   Human :100%,   Mouse :92%,   Rat :92%,  
Characteristics This is a rabbit polyclonal antibody against SNRP70. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name SNRP70
Background SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Molecular Weight 51kDa
Gene ID 6625
NCBI Accession NP_003080, NM_003089
UniProt P08621
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-SNRP70 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Brandenberger, Wei, Zhang et al.: "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation." in: Nature biotechnology, Vol. 22, Issue 6, pp. 707-16, 2004 (PubMed).

Dieker, Cisterna, Monneaux et al.: "Apoptosis-linked changes in the phosphorylation status and subcellular localization of the spliceosomal autoantigen U1-70K." in: Cell death and differentiation, Vol. 15, Issue 4, pp. 793-804, 2008 (PubMed).

Alternatives for antigen "Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70)", type "Antibodies"
Hosts (13), (4), (1)
Reactivities (15), (2), (2), (2), (2), (2), (2)
Applications (14), (6), (5), (1)
Epitopes (4), (2), (1), (1), (1), (1)
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