Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN185460

Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (C-Term) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms FSGS2, TRP6, AV025995, LLHWJM002, LLHWJM003, LLHWJM004, TRP-6, Trrp6, mtrp6, trp6, bZ1P14.9, si:rp71-1p14.9, trpc6
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Mouse (Murine)
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN185460
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
Shipping to
Availability Ships within 5 Business Days
Immunogen Peptide with sequence C-EKLSMEPNQEETN, from the C Terminus of the protein sequence according to NP_004612.2.
Cross-Reactivity Human, Dog (Canine), Pig (Porcine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name TRPC6
Background Synonyms: TRPC6, transient receptor potential cation channel, subfamily C, member 6, HGNC:12338, TRP6, transient receptor potential channel 6, FLJ11098, FLJ14863, FSGS2, TRP6
Gene ID 7225
NCBI Accession NP_004612.2
Research Area Signaling
Application Notes ELISA: antibody detection limit dilution 1:2000.
Western blot: Preliminary experiments gave an approx 80 kDa band in Human Spleen and Testis lysates after 1 µg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 106 kDa according to NP_004612.2. The 80 kDa band was successfully blocked by incubation with the immunizing peptide. Flow cytometry: This antibody has been proven to specifically react to TRPC6 in FC.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Winn, Conlon, Lynn et al.: "A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis." in: Science (New York, N.Y.), Vol. 308, Issue 5729, pp. 1801-4, 2005 (PubMed).

Alternatives for antigen "Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6)", type "Antibodies"
Hosts (77), (12), (5), (1), (1)
Reactivities (79), (57), (45), (19), (19), (19), (17), (4), (2), (1), (1), (1)
Applications (71), (33), (25), (18), (16), (10), (2), (2), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (23), (18), (3), (2), (2), (1), (1)
Beacon