TRPC6 antibody (AA 500-600)

Catalog No. ABIN6149580

The Rabbit Polyclonal anti-TRPC6 antibody is suitable to detect TRPC6 in samples from Human. It has been validated for WB and IHC.

Quick Overview for TRPC6 antibody (AA 500-600) (ABIN6149580)

Target: TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPC6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TRPC6 Antibody

Binding Specificity: AA 500-600

Sequence: SWVIGMIWAE CKEIWTQGPK EYLFELWNML DFGMLAIFAA SFIARFMAFW HASKAQSIID ANDTLKDLTK VTLGDNVKYY NLARIKWDPS DPQIISEGLY A

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TRPC6 (NP_004612.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRPC6

Target: TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))

Alternative Name: TRPC6

Background: The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).,TRPC6,FSGS2,TRP6,Signal Transduction,Neuroscience,Calcium Signaling,TRPC6

Molecular Weight: 93 kDa/100 kDa/106 kDa

Gene ID: 7225

UniProt: Q9Y210