TRPC6 antibody (C-Term)
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- Target See all TRPC6 Antibodies
- TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TRPC6 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse
- Characteristics
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Rabbit polyclonal antibody to TRPC6 (transient receptor potential cation channel, subfamily C, member 6)
TRPC6 antibody [C3], C-term - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TRPC6. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product TRPC6 Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: HeLaS3 , A549 membrane fraction extract
Validation: Orthogonal
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
- Alternative Name
- transient receptor potential cation channel subfamily C member 6 (TRPC6 Products)
- Synonyms
- FSGS2 antibody, TRP6 antibody, AV025995 antibody, LLHWJM002 antibody, LLHWJM003 antibody, LLHWJM004 antibody, TRP-6 antibody, Trrp6 antibody, mtrp6 antibody, trp6 antibody, bZ1P14.9 antibody, si:rp71-1p14.9 antibody, trpc6 antibody, transient receptor potential cation channel subfamily C member 6 antibody, transient receptor potential cation channel, subfamily C, member 6 antibody, transient receptor potential cation channel, subfamily C, member 6a antibody, TRPC6 antibody, Trpc6 antibody, trpc6a antibody, trpc6 antibody
- Background
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The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Cellular Localization: Membrane, Multi-pass membrane protein - Molecular Weight
- 106 kDa
- Gene ID
- 7225
- UniProt
- Q9Y210
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