TNFRSF1B antibody

Catalog No. ABIN199777

Product Details anti-TNFRSF1B Antibody

Target: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: Recognizes the extracellular part of human TNF-R II and with the soluble receptor. Minimal cross-reactivity is present with human TNF-alpha.

Purification: Purified

Immunogen: Human CD120b.

Type of Immunogen: Purified protein

Isotype: IgG

Application Details

Application Notes: Approved: ELISA, Flo (1:10), IP, WB (1:10)

Usage: Suitable for use in ELISA, Western Blot, Flow Cytometry and Immunoprecipitation. The antibody is an agonistic antibody useful for detection of TNF-R II. The reactivity of the antibodies with cell bound or soluble TNF-Receptor is not inhibited by high concentrations of TNF-alpha. Western Blot: 1:10. Flow Cytometry: 1:10. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.1 % BSA, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for TNFRSF1B

Target: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Alternative Name: TNFRSF1B / TNFR2 / p75 (TNFRSF1B Products)

Background: Name/Gene ID: TNFRSF1B
Family: TNF Receptor

Synonyms: TNFRSF1B, CD120b antigen, CD120b, Etanercept, p75 TNF receptor, Soluble TNFR1B variant 1, TNFBR, Tumor necrosis factor receptor, TNF-R-II, TNF-R75, TNFR2, p75TNFR, p80 TNF-alpha receptor, TBPII, TNF-R2, TNFR80, TNF-RII, TNFR-II, TNFR1B

Gene ID: 7133

UniProt: P20333

Pathways: NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway