TNFRSF1B antibody (C-Term)
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- Target See all TNFRSF1B Antibodies
- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNFRSF1B antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from C-terminal of Human TNF Receptor II.
- Isotype
- IgG
- Top Product
- Discover our top product TNFRSF1B Primary Antibody
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- Application Notes
- WB:1:500-1:3000, IF:1:100-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
- Alternative Name
- TNFRSF1B (TNFRSF1B Products)
- Synonyms
- CD120b antibody, TBPII antibody, TNF-R-II antibody, TNF-R75 antibody, TNFBR antibody, TNFR1B antibody, TNFR2 antibody, TNFR80 antibody, p75 antibody, p75TNFR antibody, TNF-RII/TNFRSF1B antibody, TNFR-II antibody, TNFRSF1B antibody, TNF-R2 antibody, TNF-alphaR2 antibody, TNFRII antibody, TNFalpha-R2 antibody, Tnfr-1 antibody, Tnfr2 antibody, rank antibody, zgc:163064 antibody, TNF receptor superfamily member 1B antibody, tumor necrosis factor receptor superfamily, member 1b antibody, tumor necrosis factor receptor superfamily, member 1B antibody, TNFRSF1B antibody, Tnfrsf1b antibody, tnfrsf1b antibody
- Background
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Background: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Smith C.A., Science 248:1019-1023(1990).
Kohno T., Proc. Natl. Acad. Sci. U.S.A. 87:8331-8335(1990).
Beltinger C.P., Genomics 35:94-100(1996).Aliases: CD120b antibody, p75 antibody, p75 TNF receptor antibody, p75TNFR antibody, p80 TNF alpha receptor antibody, p80 TNF-alpha receptor antibody, Soluble TNFR1B variant 1 antibody, TBP-2 antibody, TBPII antibody, TNF R II antibody, TNF R2 antibody, TNF R75 antibody, TNF-R2 antibody, TNF-RII antibody, TNFBR antibody, TNFR-II antibody, TNFR1B antibody, TNFR2 antibody, TNFR80 antibody, TNFRII antibody, Tnfrsf1b antibody, TNR1B_HUMAN antibody, Tumor necrosis factor beta receptor antibody, Tumor necrosis factor binding protein 2 antibody, Tumor necrosis factor receptor 2 antibody, Tumor necrosis factor receptor superfamily member 1B antibody, Tumor necrosis factor receptor type II antibody, Tumor necrosis factor-binding protein 2 antibody
- UniProt
- P20333
- Pathways
- NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway
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