IL-6 Receptor antibody

Catalog No. ABIN208780

Product Details anti-IL-6 Receptor Antibody

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-6 Receptor antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificity: Specifically recognizes soluble and membrane bound human IL-6 receptor gp80. This antibody binds to the IL-6 receptor in the presence of IL-6. This antibody was studied at the Fifth Leukocyte Typing Workshop.

Purification: Ion exchange chromatography

Immunogen: CHO cells transfected with cDNA produced from the gp80 IL-6 receptor mRNA.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA (1 μg/mL), Flo, ICC

Usage: Suitable for use in Flow Cytometry, ELISA and Immunocytochemistry. Note: Further dilutions should be made with PBS, 0.1-1 % BSA.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS. No preservatives added.

Preservative: Without preservative

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: IL6R / IL6 Receptor (IL6R Products)

Background: Name/Gene ID: IL6R
Family: Interleukin

Synonyms: IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ

Gene ID: 3570

UniProt: P08887

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints