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CD40 Ligand antibody

CD40LG Reactivity: Mouse FACS, IP, Func Host: Hamster Monoclonal MR1 unconjugated

Catalog No. ABIN226479

Datasheet as PDF

Target See all CD40 Ligand (CD40LG) Antibodies

CD40 Ligand (CD40LG)
Reactivity
147

77

34

9

8

6

5

2

2

2

2

1

1

1

1
Mouse
Host
94

65

21

11

10

2
Hamster
Clonality
111

87

4
Monoclonal
Conjugate
107

23

20

14

7

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD40 Ligand antibody is un-conjugated
Application
106

100

55

50

39

29

21

17

16

14

13

13

6

4

4

4

4

3

3

2

2

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Specificity

Recognizes CD154 (mouse CD40 ligand/gp39), Mr 39kD. Binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens, yet does not alter the immune response to TI antigens.

Purification

Purified

Immunogen

Activated mouse Th1 clone D1.6.

Type of Immunogen: Cells

Clone

MR1

Isotype

IgG kappa

Top Product

Discover our top product CD40LG Primary Antibody
anti-CD40 Ligand (CD40LG) (AA 1-261) antibody
CD40LG Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 108-261) antibody
CD40LG Reactivity: Human FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal CD40LG-2761 unconjugated

anti-CD40 Ligand (CD40LG) (AA 108-261) antibody
CD40LG Reactivity: Human FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal CD40LG-2763 unconjugated

anti-CD40 Ligand (CD40LG) antibody (FITC)
CD40LG Reactivity: Mouse FACS Host: Armenian Hamster Monoclonal MR-1 FITC

anti-CD40 Ligand (CD40LG) (AA 33-62), (N-Term) antibody
CD40LG Reactivity: Human WB, FACS, IF, IHC (p) Host: Rabbit Polyclonal RB19150 unconjugated

anti-CD40 Ligand (CD40LG) (AA 79-129) antibody
CD40LG Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 33-62) antibody
CD40LG Reactivity: Human WB, FACS, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 111-261) antibody
CD40LG Reactivity: Pig WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) antibody (PE)
CD40LG Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal 24-31 PE

anti-CD40 Ligand (CD40LG) (AA 47-261) antibody
CD40LG Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 8H10F5 unconjugated

Application Notes

Approved: Flo, Func, IP

Usage: Suitable for use in Flow Cytometry, Immunoprecipitation and in vivo and in vitro blockage of CD154 function. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment

Target Species of Antibody: Mouse

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

PBS. No preservative added.

Preservative

Azide free

Storage

4 °C,-20 °C

Storage Comment

Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
Target

CD40 Ligand (CD40LG)

Alternative Name

CD40LG / CD40L / CD154 (CD40LG Products)

Background

Name/Gene ID: CD40LG
Family: TNF

Synonyms: CD40LG, CD154, CD154 antigen, CD40-L, CD40 ligand, CD40L, gp39, HIGM1, IGM, IMD3, T-BAM, TNFSF5, CD40 antigen ligand, CD54, HCD40L, T-B cell-activating molecule, T-cell antigen Gp39, TNF-related activation protein

Gene ID

959

UniProt

P29965

Pathways

NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints