Catalase antibody
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- Target See all Catalase (CAT) Antibodies
- Catalase (CAT)
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Reactivity
- Human, Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Catalase antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Characteristics
- Homo sapiens catalase (CAT)
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human CAT (NP_111743) produced in HEK293T cell.
- Clone
- 1B8
- Isotype
- IgG1
- Top Product
- Discover our top product CAT Primary Antibody
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- Application Notes
- WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- Catalase (CAT)
- Alternative Name
- CAT (CAT Products)
- Background
- This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
- Molecular Weight
- 59.6 kDa
- Gene ID
- 847
- NCBI Accession
- NM_001752
- HGNC
- 847
- Pathways
- Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism
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