DC-SIGN/CD209 antibody

Catalog No. ABIN2479243

Product Details anti-DC-SIGN/CD209 Antibody

Target: DC-SIGN/CD209 (CD209) (CD209)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DC-SIGN/CD209 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Characteristics: Purified IgG

Endotoxin Level: Low endotoxin

Clone: MR-1

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-DC-SIGN/CD209 antibody (ABIN2479243)

Domínguez-Soto, Sierra-Filardi, Puig-Kröger, Pérez-Maceda, Gómez-Aguado, Corcuera, Sánchez-Mateos, Corbí: "Dendritic cell-specific ICAM-3-grabbing nonintegrin expression on M2-polarized and tumor-associated macrophages is macrophage-CSF dependent and enhanced by tumor-derived IL-6 and IL-10." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 4, pp. 2192-200, (2011) (PubMed).

Relloso, Puig-Kröger, Pello, Rodríguez-Fernández, de la Rosa, Longo, Navarro, Muñoz-Fernández, Sánchez-Mateos, Corbí: "DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-beta, and anti-inflammatory agents." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 6, pp. 2634-43, (2002) (PubMed).

Melero, Gabari, Corbí, Relloso, Mazzolini, Schmitz, Rodriguez-Calvillo, Tirapu, Camafeita, Albar, Prieto: "An anti-ICAM-2 (CD102) monoclonal antibody induces immune-mediated regressions of transplanted ICAM-2-negative colon carcinomas." in: Cancer research, Vol. 62, Issue 11, pp. 3167-74, (2002) (PubMed).

Target Details for DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Alternative Name: CD209 (CD209 Products)

Background: Synonyms: DC-SIGN

Gene ID: 30835

UniProt: Q9NNX6