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CD40 Ligand antibody (PE)
CD40LG
Reactivity: Mouse
FACS
Host: Hamster
Monoclonal
MR1
PE
Product Details anti-CD40 Ligand Antibody (PE)
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Target
See all CD40 Ligand (CD40LG) Antibodies
CD40 Ligand (CD40LG)
Reactivity
All reactivities for CD40 Ligand antibodies
Mouse
Host
All hosts for CD40 Ligand antibodies
Hamster
Clonality
All clonalities for CD40 Ligand antibodies
Monoclonal
Conjugate
All conjugates for CD40 Ligand antibodies
This CD40 Ligand antibody is conjugated to PE
Application
All applications for CD40 Ligand antibodies
Flow Cytometry (FACS)
Specificity
The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39.
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clone
MR1
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.2 mg/mL
Buffer
Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Storage
4 °C
Storage Comment
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target Details for CD40 Ligand
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Target
CD40 Ligand (CD40LG)
Alternative Name
CD154 (CD40LG Products )
Background
The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39. CD154 is expressed on activated T cells and plays a role in B-T cell costimulation. The interaction of CD154 with CD40 induces B cell cycle entry and the signaling for T-dependent B cell activation. By interfering with this interaction, the MR1 antibody is reported to inhibit T and B lymphocyte activation.
Gene ID
21947
UniProt
P27548
Pathways
NF-kappaB Signaling , Production of Molecular Mediator of Immune Response , Cancer Immune Checkpoints
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