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Integrin beta 3 antibody

ITGB3 Reactivity: Human WB, FACS, IHC, Func Host: Mouse Monoclonal VI-PL2 unconjugated

Catalog No. ABIN2567868

Datasheet as PDF

Target See all Integrin beta 3 (ITGB3) Antibodies

Integrin beta 3 (ITGB3)
Reactivity
176

92

60

16

15

13

12

9

8

8

5

2

2

2

1

1

1

1
Human
Host
119

60

11

2
Mouse
Compatible Secondaries
Clonality
114

76
Monoclonal
Conjugate
99

16

11

10

6

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This Integrin beta 3 antibody is un-conjugated
Application
120

82

51

45

29

28

23

19

15

13

13

5

5

3

3

2

2

2

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)

Specificity

The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3.

Purification

The monoclonal antibody was purified utilizing affinity chromatography.

Clone

VI-PL2

Isotype

IgG1 kappa

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anti-Integrin beta 3 (ITGB3) (AA 27-120) antibody
ITGB3 Reactivity: Human, Mouse WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 27-179) antibody
ITGB3 Reactivity: Human FACS, IHC, ELISA Host: Mouse Monoclonal 3E8A6 unconjugated

anti-Integrin beta 3 (ITGB3) antibody
ITGB3 Reactivity: Human WB, IHC, IP Host: Rabbit Monoclonal unconjugated

anti-Integrin beta 3 (ITGB3) antibody (FITC)
ITGB3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal VIPL2 FITC

anti-Integrin beta 3 (ITGB3) antibody (PerCP)
ITGB3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal VIPL2 PerCP

anti-Integrin beta 3 (ITGB3) (AA 385-490) antibody
ITGB3 Reactivity: Human IHC, StM Host: Mouse Monoclonal ITGB3-2145 unconjugated

anti-Integrin beta 3 (ITGB3) (AA 610-718) antibody
ITGB3 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 734-760) antibody
ITGB3 Reactivity: Human WB, FACS, IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) antibody
ITGB3 Reactivity: Human, Non-Human Primate WB, FACS, IHC (fro) Host: Mouse Monoclonal VIPL2 unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

0.5 mg/mL

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage

4 °C

Storage Comment

The product should be stored undiluted at 4°C. Do not freeze.
Target

Integrin beta 3 (ITGB3)

Alternative Name

CD61 (ITGB3 Products)

Background

The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3. CD61 forms a complex with CD41 (platelet gpIIb) and CD51 (integrin alphaV). It is expressed on osteoclasts, fibroblasts, platelets, macrophages, and megakaryocytes and appears to bind to fibronectin, vitronectin, thrombospondin, and fibrinogen and vWF. The VI-PL2 antibody is reported to be cross-reactive with baboon, rhesus, and cynomolgus.

Gene ID

3690

UniProt

P05106

Pathways

Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex