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CD40 Ligand antibody (FITC)
CD40LG
Reactivity: Human
FACS
Host: Mouse
Monoclonal
24-31
FITC
Product Details anti-CD40 Ligand Antibody (FITC)
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Target
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CD40 Ligand (CD40LG)
Reactivity
All reactivities for CD40 Ligand antibodies
Human
Host
All hosts for CD40 Ligand antibodies
Mouse
Clonality
All clonalities for CD40 Ligand antibodies
Monoclonal
Conjugate
All conjugates for CD40 Ligand antibodies
This CD40 Ligand antibody is conjugated to FITC
Application
All applications for CD40 Ligand antibodies
Flow Cytometry (FACS)
Cross-Reactivity
Cynomolgus, Rhesus Monkey
Purification
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone
24-31
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CD40 Ligand
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Target
CD40 Ligand (CD40LG)
Alternative Name
CD154 (CD40LG Products )
Background
CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.
Pathways
NF-kappaB Signaling , Production of Molecular Mediator of Immune Response , Cancer Immune Checkpoints
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