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Integrin beta 3 antibody

Name: Integrin beta 3 antibody
SKU: ABIN2664785
Availability: OutOfStock

ITGB3 Reactivity: Mouse, Rat FACS Host: Hamster Monoclonal 2C9-G2 (HMbeta3-1) unconjugated

FACS

1 image

Catalog No. ABIN2664785

Datasheet as PDF

Target See all Integrin beta 3 (ITGB3) Antibodies

Integrin beta 3 (ITGB3)
Reactivity
180

92

60

16

15

13

12

9

8

8

5

2

2

2

1

1

1

1
Mouse, Rat
Host
120

63

11

2
Hamster
Clonality
115

79
Monoclonal
Conjugate
103

16

11

10

6

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This Integrin beta 3 antibody is un-conjugated
Application
122

85

53

46

29

28

23

19

15

13

13

5

5

3

3

3

2

2

1
Flow Cytometry (FACS)

Purification

The antibody was purified by affinity chromatography.

Clone

2C9-G2 (HMbeta3-1)

Isotype

IgG

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ITGB3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal VIPL2 FITC

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ITGB3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal VIPL2 PerCP

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ITGB3 Reactivity: Human IHC, StM Host: Mouse Monoclonal ITGB3-2145 unconjugated

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ITGB3 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

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ITGB3 Reactivity: Human WB, FACS, IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) antibody
ITGB3 Reactivity: Human, Non-Human Primate WB, FACS, IHC (fro) Host: Mouse Monoclonal VIPL2 unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Concentration

0.5 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Storage Comment

The antibody solution should be stored undiluted between 2°C and 8°C.
Target

Integrin beta 3 (ITGB3)

Alternative Name

CD61 (ITGB3 Products)

Background

CD61 is a 110 kD integrin β chain also known as β3 integrin or gpIIIa. It associates with the integrin αv chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate with the integrin αIIb chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets, megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts, and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelial adhesion is mediated by the binding of αv/β3 integrin or vitronectin receptor to CD31 (PECAM-1).

Pathways

Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex