CCR7 antibody (AA 2-22)
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- Target See all CCR7 Antibodies
- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
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Binding Specificity
- AA 2-22
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Reactivity
- Mouse
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This CCR7 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunochromatography (IC)
- Cross-Reactivity
- Human
- Cross-Reactivity (Details)
- Peptide sequence is <50 % identical to other mouse chemokine receptors inthis region and crossreacts with human CCR7
- Immunogen
- CCR7 antibody was raised in goat using a synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acid residues 2-22 of mouse CCR7 as the immunogen.
- Isotype
- IgG1
- Top Product
- Discover our top product CCR7 Primary Antibody
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- Application Notes
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ELISA: 1:100,000, FC: 1:10, IC: 1:250, IHC: 1:250, WB: 1:1,000
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
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- Concentration
- Lot specific
- Buffer
- 10 mM KHPO4, pH 7.2, with 140 M NaCl, 1 mg/mL BSA and 0.1 % NaN3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- -20 °C/-80 °C
- Storage Comment
- Aliquot and store at -20 °C for short term storage, -70 °C for long-term storage.
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- Target
- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
- Alternative Name
- CCR7 (CCR7 Products)
- Background
- C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. CCR7 has also recently been designated CD197 (cluster of differentiation 197). The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes.
- Pathways
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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