CCR7 antibody (AA 11-37)

Catalog No. ABIN3030497

Product Details anti-CCR7 Antibody

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Binding Specificity: AA 11-37

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR7 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 11-37 from the human protein was used as the immunogen for this CCR7 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CCR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CCR7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CCR7

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Alternative Name: CCR7 (CCR7 Products)

Synonyms: zgc:165629 antibody, ccr7-a antibody, CD197 antibody, Cdw197 antibody, Cmkbr7 antibody, EBI1 antibody, Ebi1h antibody, BLR2 antibody, CDw197 antibody, CMKBR7 antibody, chemokine (C-C motif) receptor 7 antibody, C-C motif chemokine receptor 7 antibody, C-C motif chemokine receptor 7 L homeolog antibody, ccr7 antibody, CCR7 antibody, ccr7.L antibody, Ccr7 antibody

Background: CCR7 is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.

UniProt: P32248

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process