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ICAM-1 antibody (Intercellular Adhesion Molecule 1)

Details for Product anti-ICAM1 Antibody No. ABIN302240, Supplier: Login to see New
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Synonyms BB2, CD54, P3.58, Icam-1, Ly-47, MALA-2, ICAM, ICAM-1, ICAM1
(609), (147), (112), (11), (10), (7), (1), (1), (1)
(447), (257), (78), (10), (9), (5), (4), (2)
Clonality (Clone)
Monoclonal ()
This ICAM-1 antibody is un-conjugated
(81), (80), (71), (21), (10), (10), (8), (8), (6), (4), (4), (4), (4), (4), (4), (3), (3), (2), (1), (1), (1)
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(410), (312), (192), (162), (162), (111), (110), (59), (49), (40), (37), (15), (12), (12), (10), (9), (6), (6), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Raji cells and spleen cells fused with NS1 cells
Clone 1H4
Isotype IgG2b
Characteristics Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
Purification Protein A Affinity Chromatography
Alternative Name CD54 / ICAM1 (ICAM1 Antibody Abstract)
Background CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
UniProt P05362
Application Notes Flow Cytometry. Western blot. Immunohistochemistry (paraffin sections): 10-20 μg/mL (Prolonged fixation in bufferedformalin can destroy the epitope, hight temperature antigen unmasking technique isrequired). Immunohistochemistry (frozen sections): 5-20 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer Azide free PBS preserved by filter sterilization, pH ~7.4
Preservative Azide free
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-ICAM-1 antibody (Intercellular Adhesion Molecule 1) (ABIN302240) anti-Intercellular Adhesion Molecule 1 (ICAM1) antibody
Background publications Williams, Chaudhry, Goodfellow et al.: "Interactions of decay-accelerating factor (DAF) with haemagglutinating human enteroviruses: utilizing variation in primate DAF to map virus binding sites." in: The Journal of general virology, Vol. 85, Issue Pt 3, pp. 731-8, 2004 (PubMed).

Boyd, Wawryk, Burns et al.: "Intercellular adhesion molecule 1 (ICAM-1) has a central role in cell-cell contact-mediated immune mechanisms." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 9, pp. 3095-9, 1988 (PubMed).

Boyd, Dunn, Fecondo et al.: "Regulation of expression of a human intercellular adhesion molecule (ICAM-1) during lymphohematopoietic differentiation." in: Blood, Vol. 73, Issue 7, pp. 1896-903, 1989 (PubMed).

Springer: "Adhesion receptors of the immune system." in: Nature, Vol. 346, Issue 6283, pp. 425-34, 1990 (PubMed).

Ockenhouse, Betageri, Springer et al.: "Plasmodium falciparum-infected erythrocytes bind ICAM-1 at a site distinct from LFA-1, Mac-1, and human rhinovirus." in: Cell, Vol. 68, Issue 1, pp. 63-9, 1992 (PubMed).

Catalog No. ABIN302240
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