SLC44A1 antibody (PE)

Catalog No. ABIN316974

Product Details anti-SLC44A1 Antibody (PE)

Target: SLC44A1 (Solute Carrier Family 44, Member 1 (SLC44A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC44A1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: This antibody is specific for the C-terminal variant of human CDw92 (isoform 3), also known as CTL1. Clone VIM-15b is reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells (Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10.

Characteristics: Synonyms: CDw92, CTL1, Choline transporter-like protein 1, Solute carrier family 44 member 1

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: MV4-11 acute monocyte leukaemia cells.

Clone: VIM-15b

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry: 1/10.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute with 1.0 mL distilled water

Concentration: 0,1 mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3) and 1 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for SLC44A1

Target: SLC44A1 (Solute Carrier Family 44, Member 1 (SLC44A1))

Alternative Name: CD92 / SLC44A1 (SLC44A1 Products)

Background: CDw92 is a 70 kDa multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells. CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine.Synonyms: CDw92, CTL1, Choline transporter-like protein 1, Solute carrier family 44 member 1

Gene ID: 23446

UniProt: Q8WWI5