SLC44A1 antibody (PE)

Catalog No. ABIN7505966

The PE-conjugated Mouse Monoclonal anti-SLC44A1 antibody (Clone VIM15) (ABIN7505966) specifically detects SLC44A1 in FACS. The antibody is reactive with Human samples.

Quick Overview for SLC44A1 antibody (PE) (ABIN7505966)

Target: SLC44A1 (Solute Carrier Family 44, Member 1 (SLC44A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC44A1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: VIM15

Product Details anti-SLC44A1 Antibody (PE)

Purpose: Anti-Hu CD92 PE

Characteristics: The mouse monoclonal antibody VIM15 recognizes an extracellular epitope of CD92, a 70 kDa transmembrane glycoprotein expressed mainly on human peripheral blood monocytes and neutrophils, and several myeloid and T-cell lines.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: MV4-11 acute myeloid leukemia cells

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze,Protect from prolonged exposure to light

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for SLC44A1

Target: SLC44A1 (Solute Carrier Family 44, Member 1 (SLC44A1))

Alternative Name: CD92

Background: Solute carrier family 44 member 1,CD92 is a 70 kDa protein with ten transmembrane domains, intracellular N and C teminus, and two glycosylated larger extracellular loops. In the C-terminal domain, there is an ITIM-like sequence. This protein seems to be a choline transporter responsible for delivery of choline into the immune cells, to make it accessible for phospholipid synthesis, as well as a regulator of immune cell signaling. It is expressed mainly on human peripheral blood monocytes and neutrophils, and several myeloid and T-cell lines. It can also be found on mast cells (but not eosinophils), and weakly on peripheral blood lymphocytes, fibroblasts, epithelial cells, and endothelial cells.,CTL1, CHTL1, SLC44A1

Gene ID: 23446

UniProt: Q8WWI5