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Details for Product No. ABIN334371

Centrosomal Protein 290kDa (CEP290) (Internal Region) antibody

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Antigen
Synonyms 3H11Ag, BBS14, CT87, JBTS5, LCA10, MKS4, NPHP6, POC3, SLSN6, rd16, RGD1311640, BC004690, Nphp6, b2b1454Clo, b2b1752Clo, ct87, mks4, bbs14, jbts5, jbts6, lca10, nphp6, slsn6, sh11ag, MGC81471, 3h11ag
Epitope
»Alternatives Internal Region
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN334371
Quantity 100 µg
Price
261.61 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-QSGAESTIPDADQ, from the internal region of the protein sequence according to NP_079390.3.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name CEP290 / NPHP6
Background Synonyms: CEP290, centrosomal protein 290kDa, 3H11Ag, FLJ13615, FLJ21979, JBTS5, JBTS6, KIAA0373, LCA10, MKS4, NPHP6, SLSN6, rd16, CTCL tumor antigen se2-2, monoclonal 3H11 antigen, nephrocystin 6, nephrocystin-6, nephrocytsin-6, prostate cancer antigen T21
Gene ID 80184
NCBI Accession NP_079390.3
Application Notes ELISA: antibody detection limit dilution 1:8000.
Western blot: Preliminary experiments in Human Kidney, Ovary and Thymus lysates gave no specific signal but low background (at antibody concentration up to 1 µg/mL).
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
McEwen, Koenekoop, Khanna et al.: "Hypomorphic CEP290/NPHP6 mutations result in anosmia caused by the selective loss of G proteins in cilia of olfactory sensory neurons." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 40, pp. 15917-22, 2007 (PubMed).

Alternatives for antigen "Centrosomal Protein 290kDa (CEP290)", type "Antibodies"
Hosts (14), (7)
Reactivities (19), (13), (4)
Applications (15), (15), (4), (1), (1), (1), (1)
Epitopes (5), (2), (1)
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