Centrosomal Protein 290kDa (CEP290) (Internal Region) antibody

Details for Product No. ABIN334371
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Synonyms 3H11Ag, BBS14, CT87, JBTS5, LCA10, MKS4, NPHP6, POC3, SLSN6, rd16, RGD1311640, BC004690, Nphp6, b2b1454Clo, b2b1752Clo, ct87, mks4, bbs14, jbts5, jbts6, lca10, nphp6, slsn6, sh11ag, MGC81471, 3h11ag
Internal Region
(6), (2), (1)
(18), (14), (4)
(14), (6)
Methode Type Peptide ELISA
ELISA, Western Blotting (WB)
(15), (15), (4), (1), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN334371
Quantity 100 µg
261.61 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-QSGAESTIPDADQ, from the internal region of the protein sequence according to NP_079390.3.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name CEP290 / NPHP6
Background Synonyms: CEP290, centrosomal protein 290kDa, 3H11Ag, FLJ13615, FLJ21979, JBTS5, JBTS6, KIAA0373, LCA10, MKS4, NPHP6, SLSN6, rd16, CTCL tumor antigen se2-2, monoclonal 3H11 antigen, nephrocystin 6, nephrocystin-6, nephrocytsin-6, prostate cancer antigen T21
Gene ID 80184
NCBI Accession NP_079390.3
Application Notes ELISA: antibody detection limit dilution 1:8000.
Western blot: Preliminary experiments in Human Kidney, Ovary and Thymus lysates gave no specific signal but low background (at antibody concentration up to 1 µg/mL).
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
General McEwen, Koenekoop, Khanna et al.: "Hypomorphic CEP290/NPHP6 mutations result in anosmia caused by the selective loss of G proteins in cilia of olfactory sensory neurons." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 40, pp. 15917-22, 2007 (PubMed).

Hosts (14), (6)
Reactivities (18), (14), (4)
Applications (15), (15), (4), (1), (1), (1)
Epitopes (6), (2), (1)
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