Dopamine Receptor D5 (DRD5) (Internal Region) antibody

Details for Product No. ABIN334388
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Antigen
Synonyms DRD5, DBDR, DRD1B, DRD1L2, D1B, D5R, Drd-5, Drd1b, Gpcr1
Epitope
Internal Region
(12), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(40), (35), (24), (1), (1)
Host
Goat
(46), (12), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB)
(37), (13), (12), (12), (10), (6), (3), (3), (2), (1)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN334388
261.61 $
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Immunogen Peptide with sequence C-NREVDNDEEEGPFD, from the internal region of the protein sequence according to NP_000789.1.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name DRD5
Background Synonyms: DRD5, dopamine receptor D5, DBDR, DRD1B, DRD1L2, MGC10601, D1beta dopamine receptor, dopamine receptor D1B
Gene ID 1816
NCBI Accession NP_000789
Application Notes ELISA: antibody detection limit dilution 1:128000.
Western blot: Preliminary experiments gave an approx 75-80 kDa band in lysates of Human Brain (hippocampus), Kidney, Spleen and Thymus after 0.1 µg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 53.0 kDa according to NP_000789.1. The 75-80 kDa band was successfully blocked by incubation with the immunizing peptide.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
General Daly, Hawi, Fitzgerald et al.: "Mapping susceptibility loci in attention deficit hyperactivity disorder: preferential transmission of parental alleles at DAT1, DBH and DRD5 to affected children." in: Molecular psychiatry, Vol. 4, Issue 2, pp. 192-6, 1999 (PubMed).

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