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Details for Product No. ABIN350476

MAP-2 antibody

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Antigen
Synonyms MAP2A, MAP2B, MAP2C, MAP-2, Mtap-2, Mtap2, MAP2R
Reactivity
»Alternatives Rat (Rattus), Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 6 references available
Catalog no. ABIN350476
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide as a part of rat, mouse Mtap2 (Microtubule-associated protein 2, MAP-2, MAP 2, MAP2, MAP2R) conjugated to an immunogenic carrier protein was used as the immunogen.
Isotype IgG
Specificity Appears to be specific for MAP-2.
Purification The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Purity IgG
Alternative Name Mtap2 (Microtubule-associated protein 2, MAP-2, MAP2R)
Background Regulates and organizes microtubules, may serve as a scaffolding protein for neuromodulatory activities.
Function: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Subcellular location: Cytoplasm, cytoskeleton.
Developmental stage: Isoform MAP2C is expressed during embryonic brain development and until postanatal day 10. Isoform MAP2B is expressed throughout brain development. Also known as: Microtubule-associated protein 2, MAP 2, MAP-2, MAP2R.
UniProt P15146
Application Notes IHC, WB. A working concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Kindler, Schulz, Goedert et al.: "Molecular structure of microtubule-associated protein 2b and 2c from rat brain." in: The Journal of biological chemistry, Vol. 265, Issue 32, pp. 19679-84, 1991 (PubMed).

Doll, Papandrikopoulou, Matus: "Nucleotide and amino acid sequences of embryonic rat MAP2c." in: Nucleic acids research, Vol. 18, Issue 2, pp. 361, 1990 (PubMed).

Kindler, Schwanke, Schulz et al.: "Complete cDNA sequence encoding rat high and low molecular weight MAP2." in: Nucleic acids research, Vol. 18, Issue 9, pp. 2822, 1990 (PubMed).

Papandrikopoulou, Doll, Tucker et al.: "Embryonic MAP2 lacks the cross-linking sidearm sequences and dendritic targeting signal of adult MAP2." in: Nature, Vol. 340, Issue 6235, pp. 650-2, 1989 (PubMed).

Ozer, Halpain: "Phosphorylation-dependent localization of microtubule-associated protein MAP2c to the actin cytoskeleton." in: Molecular biology of the cell, Vol. 11, Issue 10, pp. 3573-87, 2000 (PubMed).

Hoffert, Pisitkun, Wang et al.: "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 18, pp. 7159-64, 2006 (PubMed).

Alternatives for antigen "MAP-2", type "Antibodies"
Hosts (84), (78), (16), (4)
Reactivities (130), (89), (84), (72), (34), (25), (21), (5), (4), (3), (2), (2), (1)
Applications (137), (62), (56), (43), (40), (34), (29), (26), (19), (12), (6), (3), (2), (2), (2), (1)
Conjugates (7), (6), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Epitopes (14), (12), (12), (6), (5), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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