MAP2 antibody (AA 260-559)

Catalog No. ABIN3016265

There are 2+ publications for this product available. The Rabbit Polyclonal anti-MAP2 antibody is suitable to detect MAP2 in samples from Human. It has been validated for WB, IHC and IF.

Quick Overview for MAP2 antibody (AA 260-559) (ABIN3016265)

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MAP2 Antibody

Binding Specificity: AA 260-559

Sequence: DENSFSLNSS ISSSARRTTR SEPIRRAGKS GTSTPTTPGS TAITPGTPPS YSSRTPGTPG TPSYPRTPHT PGTPKSAILV PSEKKVAIIR TPPKSPATPK QLRLINQPLP DLKNVKSKIG STDNIKYQPK GGQVRILNKK IDFSKVQSRC GSKDNIKHSA GGGNVQIVTK KIDLSHVTSK CGSLKNIRHR PGGGRVKIES VKLDFKEKAQ AKVGSLDNAH HVPGGGNVKI DSQKLNFREH AKARVDHGAE IITQSPGRSS VASPRRLSNV SSSGSINLLE SPQLATLAED VTAALAKQGL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 260-559 of human MAP2 (NP_001034627.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-MAP2 antibody (ABIN3016265)

Xu, Zhang, Lu, Deng, Zhao, Zhao, Zhao: "Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan." in: Molecular neurobiology, Vol. 53, Issue 5, pp. 3494-502, (2016) (PubMed).

Wang, Zhu, Li, Yang, Xiao, Kang, Li, Zhao, Zeng, Li, Zhang, He, Ying et al.: "Crude Saponins of Panax notoginseng Have Neuroprotective Effects To Inhibit Palmitate-Triggered Endoplasmic Reticulum Stress-Associated Apoptosis and Loss of Postsynaptic Proteins in Staurosporine ..." in: Journal of agricultural and food chemistry, Vol. 64, Issue 7, pp. 1528-39, (2016) (PubMed).

Target Details for MAP2

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Alternative Name: Map2

Background: This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.,MAP2,MAP2A,MAP2B,MAP2C,Map2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Microtubules,Neuroscience,Cell Type Marker,Stem Cells,Neuron marker,Map2

Molecular Weight: 49 kDa/58 kDa/199 kDa

Gene ID: 4133

UniProt: P11137