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Details for Product No. ABIN358542

Homeodomain Interacting Protein Kinase 2 (HIPK2) (pTyr361) antibody

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Antigen
Synonyms PRO0593, Stank, 1110014O20Rik, B230339E18Rik, HIPK2, cb1009, si:dkey-16j24.2, si:dkey-239k7.1, wu:fk56d12, pro0593, MGC146781
Epitope
»Alternatives pTyr361
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA
Pubmed 4 references available
Catalog no. ABIN358542
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y361 of human HIPK2.
Specificity This antibody reacts to HIPK2 pTyr361.
Purification Protein A column, followed by two-step phosphospecific peptide affinity purification
Alternative Name HIPK2
Background HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors.
Alternate names: Homeodomain-interacting protein kinase 2
Gene ID 28996
NCBI Accession 9606
UniProt Q9H2X6
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA, Apoptosis/Necrosis
Application Notes ELISA: 1/1,000. Dot Blot: 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Guo, Villén, Kornhauser et al.: "Signaling networks assembled by oncogenic EGFR and c-Met." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 2, pp. 692-7, 2008 (PubMed).

Daub, Olsen, Bairlein et al.: "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." in: Molecular cell, Vol. 31, Issue 3, pp. 438-48, 2008 (PubMed).

Guha, Chaerkady, Marimuthu et al.: "Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 37, pp. 14112-7, 2008 (PubMed).

Alternatives for antigen "Homeodomain Interacting Protein Kinase 2 (HIPK2)", type "Antibodies"
Hosts (29), (7)
Reactivities (35), (16), (11), (11), (11), (11)
Applications (19), (16), (10), (9), (3), (3), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (4), (3), (3), (2), (1), (1), (1), (1)
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