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HIPK2 Products

(Homeodomain Interacting Protein Kinase 2 (HIPK2))
This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

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Featured HIPK2 Categories

HIPK2 Antibodies

High quality antibodies with extensive validation data.

HIPK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

HIPK2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HIPK2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (3)
  • (9)
Cat. No. ABIN2779735
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (3)
Cat. No. ABIN565400
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN565401
Quantity 100 μg
Datasheet Datasheet

Recommended HIPK2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956593
Quantity 96 tests
Datasheet Datasheet

Recommended HIPK2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570369
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306647
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3092963
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HIPK2 products

Upadhyay, Bhadauriya, Ganesh: "Heat shock modulates the subcellular localization, stability, and activity of HIPK2." in: Biochemical and biophysical research communications, Vol. 472, Issue 4, pp. 580-4, (2016) (PubMed).

Esposito, Tornincasa, Chieffi, De Martino, Pierantoni, Fusco: "High-mobility group A1 proteins regulate p53-mediated transcription of Bcl-2 gene." in: Cancer research, Vol. 70, Issue 13, pp. 5379-88, (2010) (PubMed).

Steinmann, Schulte, Beck, Chachra, Bujnicki, Klempnauer: "v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300." in: Oncogene, Vol. 28, Issue 26, pp. 2446-55, (2009) (PubMed).

Daub, Olsen, Bairlein, Gnad, Oppermann, Körner, Greff, Kéri, Stemmann, Mann: "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." in: Molecular cell, Vol. 31, Issue 3, pp. 438-48, (2008) (PubMed).

Choi, Seo, Kim, Sung, Ahn, Park, Lee, Choi: "Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1." in: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4682-9, (2008) (PubMed).

Isono, Nemoto, Li, Takada, Suzuki, Katsuki, Nakagawara, Koseki: "Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals." in: Molecular and cellular biology, Vol. 26, Issue 7, pp. 2758-71, (2006) (PubMed).

Wang, Hofmann, Runkel, Haaf, Schaller, Debatin, Hug: "Isolation and characterization of cDNAs for the protein kinase HIPK2." in: Biochimica et biophysica acta, Vol. 1518, Issue 1-2, pp. 168-72, (2001) (PubMed).

Li, Wang, Debatin, Hug: "The serine/threonine kinase HIPK2 interacts with TRADD, but not with CD95 or TNF-R1 in 293T cells." in: Biochemical and biophysical research communications, Vol. 277, Issue 2, pp. 513-7, (2000) (PubMed).

Synonyms and alternative names related to HIPK2

homeodomain interacting protein kinase 2 (HIPK2), serine/threonine kinase (Smp_000720), homeodomain interacting protein kinase 2 (hipk2), homeodomain interacting protein kinase 2 L homeolog (hipk2.L), homeodomain interacting protein kinase 2 (Hipk2), 1110014O20Rik, B230339E18Rik, cb1009, HIPK2, MGC146781, PKM, pro0593, PRO0593, si:dkey-16j24.2, si:dkey-239k7.1, Stank, wu:fk56d12

Protein level used designations for HIPK2

  • homeodomain interacting protein kinase 2
  • serine/threonine protein kinase
  • homeodomain-interacting protein kinase 2-like
  • homeodomain-interacting protein kinase 2
  • homeodomain-interacting protein kinase-2
  • hHIPk2
  • nuclear body-associated kinase 1
  • sialophorin tail-associated nuclear serine/threonine-protein kinase
  • Mx-interacting protein kinase PKM
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