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Ephrin Type A Receptor 1 (EPHA1) (N-Term) antibody

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Synonyms EPH, EPHT, EPHT1, 5730453L17Rik, AL033318, Eph, Esk, EPHA9
(28), (20), (15), (14), (12), (11), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
(107), (45), (11), (3), (3), (3), (1)
(118), (16), (1)
(8), (8), (6), (6), (6), (6)
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(122), (83), (60), (18), (17), (11), (4), (4), (2), (1)
Pubmed 3 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human EphA1.
Isotype Ig
Specificity This antibody reacts to EphA1.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name EPHA1 (EPHA1 Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: EPH, EPHT, EPHT1, Ephrin type-A receptor 1, Tyrosine-protein kinase receptor EPH
Gene ID 2041, 9606
UniProt P21709
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ephrin Type A Receptor 1 (EPHA1) (N-Term) antibody (ABIN359788) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-Ephrin Type A Receptor 1 (EPHA1) (N-Term) antibody (ABIN359788) Western blot analysis of anti-EphA1 N-term Pab in HeLa cell lysate. EphA1 (arrow) was...
Background publications Hillier, Fulton, Fulton et al.: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, 2003 (PubMed).

Owshalimpur, Kelley: "Genomic structure of the EPHA1 receptor tyrosine kinase gene." in: Molecular and cellular probes, Vol. 13, Issue 3, pp. 169-73, 1999 (PubMed).

Hirai, Maru, Hagiwara et al.: "A novel putative tyrosine kinase receptor encoded by the eph gene." in: Science (New York, N.Y.), Vol. 238, Issue 4834, pp. 1717-20, 1988 (PubMed).

Catalog No. ABIN359788
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