EPHA1 antibody (Ephrin Type A Receptor 1)

Catalog No. ABIN969478

Product Details anti-EPHA1 Antibody

Target: EPHA1

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPHA1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Purification: Purified

Immunogen: Purified recombinant fragment of EphA1 expressed in E. Coli.

Clone: 5D2

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-EPHA1 antibody (ABIN969478)

Pasquale: "Eph receptor signalling casts a wide net on cell behaviour." in: Nature reviews. Molecular cell biology, Vol. 6, Issue 6, pp. 462-75, 2005 (PubMed).

Target Details for EPHA1

Target: EPHA1

Alternative Name: EphA1 (EPHA1 Antibody Abstract)

Synonyms: EPH, EPHT, EPHT1, 5730453L17Rik, AL033318, Eph, Esk, EPHA9, EPH receptor A1, Eph receptor A1, EPHA1, Epha1

Background: EPH receptor A1 (EphA1), with 976-amino acid protein(about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins,can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.

Molecular Weight: 108 kDa

Gene ID: 2041

HGNC: 2041