CD40 Ligand antibody (FITC)
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- Target See all CD40 Ligand (CD40LG) Antibodies
- CD40 Ligand (CD40LG)
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Reactivity
- Mouse
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Host
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Hamster
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Clonality
- Monoclonal
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Conjugate
- This CD40 Ligand antibody is conjugated to FITC
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Application
- Flow Cytometry (FACS)
- Characteristics
- Synonyms: CD40 ligand, CD40-L, CD40LG, TNFSF5, TRAP, GP39, Tumor necrosis factor ligandsuperfamily member 5, TNF-related activation protein, T-cell antigen Gp39
- Immunogen
- Activated mouse Th1 clone D1. 6 (Ref. 1)
- Clone
- MR1
- Isotype
- IgG
- Top Product
- Discover our top product CD40LG Primary Antibody
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anti-CD40 Ligand (CD40LG) (AA 1-261) antibody
CD40LG Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD40 Ligand (CD40LG) (AA 108-261) antibodyCD40LG Reactivity: Human FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal CD40LG-2761 unconjugated
anti-CD40 Ligand (CD40LG) (AA 108-261) antibodyCD40LG Reactivity: Human FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal CD40LG-2763 unconjugated
anti-CD40 Ligand (CD40LG) antibody (FITC)CD40LG Reactivity: Mouse FACS Host: Armenian Hamster Monoclonal MR-1 FITC
anti-CD40 Ligand (CD40LG) (AA 33-62), (N-Term) antibodyCD40LG Reactivity: Human WB, FACS, IF, IHC (p) Host: Rabbit Polyclonal RB19150 unconjugated
anti-CD40 Ligand (CD40LG) (AA 79-129) antibodyCD40LG Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-CD40 Ligand (CD40LG) (AA 33-62) antibodyCD40LG Reactivity: Human WB, FACS, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-CD40 Ligand (CD40LG) (AA 111-261) antibodyCD40LG Reactivity: Pig WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD40 Ligand (CD40LG) antibody (PE)CD40LG Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal 24-31 PE
anti-CD40 Ligand (CD40LG) (AA 47-261) antibodyCD40LG Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 8H10F5 unconjugated
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- Application Notes
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Flow Cytometry: < / 2 μg/10^6 cells. (Ref.1,5)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.09 % Sodium Azide as preservative.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- CD40 Ligand (CD40LG)
- Alternative Name
- CD154 / CD40L (CD40LG Products)
- Background
- CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands. (Ref.1-7) It is an important accessory molecule in T cell-B cell costimulatory interactions, and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporinsensitive. (Ref.6) The MR1 monoclonal antibody binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. (Ref.1,5) Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens, yet does not alter the immune response to TI antigens. (Ref.4)Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5
- UniProt
- P27548
- Pathways
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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