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Neutrophil Cytosol Factor 1 (NCF1) (C-Term) antibody

Details for Product No. ABIN374079
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Antigen
Synonyms NCF1A, NOXO2, SH3PXD1A, p47phox, Ncf-1, p47
Epitope
C-Term
(31), (22), (9), (6), (4), (4), (2), (2), (1)
Reactivity
Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(127), (69), (57), (25), (17), (14), (4), (1), (1)
Host
Goat
(119), (11), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application
Western Blotting (WB)
(91), (83), (62), (30), (18), (17), (8), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN374079
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide from the C Terminus of the protein according to NP_000256.3. Genename: NCF1
Sequence C-SESTKRKLASAV
Specificity This antibody detects NCF-1 at C-term. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat, Rabbit, Pig, Cow.
Purification Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Alternative Name NCF1
Background NCF1, along with NCF2 and a membrane bound cytochrome b558, is required for activation of the latent NADPH oxidase necessary for superoxide production. Defects in NCF1 are the cause of autosomal cytochrome-b-positive chronic granulomatous disease type 1 (CGD).
Alternate names: 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, NCF-1, NCF-47K Neutrophil NADPH oxidase factor 1, NOXO2, Neutrophil cytosol factor 1, Nox organizer 2, Nox-organizing protein 2 SH3 and PX domain-containing protein 1A p47-phox, SH3PXD1A
Gene ID 653361
NCBI Accession NP_000256.3
UniProt P14598
Research Area Cancer, Metabolism
Application Notes Peptide ELISA: Limit dilution 1: 20000. Western blot: 0.2-2 µg/ml. Approx 47kDa band seen in U937 cell lysates. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, pH~7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Neutrophil Cytosol Factor 1 (NCF1) (C-Term) antibody anti-Neutrophil Cytosol Factor 1 (NCF1) (C-Term) antibody
Background publications Underhill, Rossnagle, Lowell et al.: "Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production." in: Blood, Vol. 106, Issue 7, pp. 2543-50, 2005 (PubMed).

Hosts (119), (11), (2)
Reactivities (127), (69), (57), (25), (17), (14), (4), (1), (1)
Applications (91), (83), (62), (30), (18), (17), (8), (2), (1)
Conjugates (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Epitopes (31), (22), (9), (6), (4), (4), (2), (2), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN374079
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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